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Due to problems with metabolism and blood circulation, oxidative processes are intensified, leading to the gradual death of tissues that receive nutrients in insufficient quantities.

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In diabetic neuropathy of the lower extremities, on average, 78% of patients develop trophic, long-healing ulcers. The disease itself develops in 60-90% of cases of diabetes during the first 5-15 years. Moreover, neuropathy occurs in people with both forms of the underlying pathology.

With peripheral neuropathy of the lower extremities, the clinical picture is diverse. This is explained by the fact that a decrease in blood sugar levels provokes damage to buy pravachol online nerve fibers. Based on this feature, a classification of the disease is built.

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The following forms of the disease are distinguished. In the central form of pathology, there are disorders associated with the functioning of the brain. The disease provokes a violation of concentration, a disorder of consciousness, dysfunction of the organs of the urinary system and intestines. Sensorimotor neuropathy is characterized by a decrease in the sensitivity of the limbs and impaired coordination of movement. Patients with this disorder have short-term convulsions. Basically, the pathology affects one limb, and the intensity of pravachol pills symptoms intensifies in the evening.

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In the late period of the development of the disease, the legs become completely numb (the patient ceases to buy pravastatin online). Due to the weakened conductivity, ulcers occur. Sensory neuropathy, unlike sensorimotor neuropathy, provokes only a decrease in sensitivity. The coordination remains the same. With motor neuropathy, accordingly, motor functions are impaired. The patient with this disorder has difficulty with movement, speech, eating.

The autonomous form of the disease occurs when the fibers of the autonomic nervous system are damaged. Because of this, the work of individual organs is disrupted.

In particular, when the vegetative system is damaged, the supply of oxygen to the body decreases, the absorption of nutrients worsens, and dysfunction of the intestines and bladder occurs. This form of the disease provokes the most diverse clinical phenomena. The proximal type of pathology is localized. The patient with this form is concerned about pain in the hip joint. As the pathological process progresses, the conductivity of nerve fibers deteriorates significantly, which leads to muscle atrophy. In advanced cases, the patient loses the ability to move.

In the focal form, individual nerve fibers are affected. This type of disease is characterized by a sudden onset. Depending on the location of the nerve fibers and the functions for which they are responsible, the patient experiences pain and paralysis of certain parts of the body (mainly one half of the face). The course of the focal form is difficult to predict. Causes of neuropathy in diabetes mellitus.

The main reason for the development of diabetic neuropathy is a change in the concentration of glucose (sugar) in the blood. This condition is not always due to non-compliance with the rules of treatment of the underlying disease. Neuropathy can be triggered by the following factors. The risk group for the development of pravachol includes people who have been diagnosed with diabetes for a long time. The older the person, the more severe the symptoms become and the more difficult it is to control the sugar level. Autonomic diabetic neuropathy is considered the most dangerous. This form of pravastatin can cause the death of the patient due to cardiac arrest. Typical symptoms of diabetic neuropathy.

The course of neuropathy in diabetes mellitus is characterized by various symptoms.

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